Cassiopeia

Once regarded as the youngest and loveliest of the Du Couteau children, Cassiopeia is no longer anyone would call beautiful. A venom-fueled transformation has stripped away the refined look of the noble daughter of Noxus she once was.

She brought this on herself through her hunger for power. Searching the crypts under Shurima for ancient strength, she was found instead by a massive tomb guardian, and its bite delivered venom strong enough to reshape her completely. She emerged as a viper-like hunter, sly and fast, able to turn foes to stone with a single look.

One link to her former self survives: her sister Katarina is still her family, even though nearly everything else about her has changed past recognition. Her remaining focus goes to scheming and to quietly pursuing her goals beneath the cover of darkness. Her abilities share that same unhurried cruelty. Serpentine Grace amplifies each point of Move Speed she collects far more than it would for anyone else. Noxious Blast poisons an area and grants her a speed boost when it hits a champion. Miasma releases poison clouds that slow and root enemies, wearing down anyone who stays inside. Twin Fang hits poisoned targets hardest, restoring some of her health based on the damage dealt, and resets its cooldown if the target dies. Petrifying Gaze, her ultimate, stuns enemies who face her head-on but only slows those who have turned their backs, a fitting design for someone whose stare is now a weapon in itself.

She usually plays mid lane, where her Mana powers both her poisons and her gaze. These are patient tools for a champion who never has to hurry. Other Noxians, including Annie, carry very different dangers, but Cassiopeia’s transformation has made her the most literally venomous of the empire’s daughters.