KDA 7/2/1 View Build
Middle Patch 16.18.1 op.gg
Cassiopeia Build
Latest Cassiopeia build for League of Legends with items, runes, summoner spells, skill order, counters and patch data.
47.66% Win Rate 1.56% Pick Rate 19,047 Games
Cassiopeia Build Guide
Mid lane is where Cassiopeia posts her numbers: a 48.88% winrate from a 1.4% pick rate on patch 16.13.1. Current ranked data calls her a demanding pick, though top lane shows up as a secondary role for players ready to adjust. Deathfire Touch serves as her keystone, layering damage over time onto her poison-stacking combos.
Start with E, follow with Q, then pick up W, since that order gets twin fang’s poison onto targets fastest. Her core runs Tear of the Goddess, Rod of Ages, and Seraph’s Embrace, a mana-scaling setup that raises her damage and durability at the same time. The full item order, rune page, and matchup counters follow below.
Cassiopeia Build
D Current tier: D Mid — view tier list
Imported from op.gg · updated every 48 hours · last update Nov 10, 2026.
Starting Items
Core Items
Boots
Full Item Set
Cassiopeia Runes — Sorcery + Precision
Deathfire Touch 
Manaflow Band 
Transcendence 
Scorch 
Presence of Mind 
Coup de Grace 
Adaptive Force Adaptive Force 
Health Scaling Cassiopeia Summoner Spells
Flash 
TeleportCassiopeia Skill Order
E › Q › W
Ability Order by Level
1E 2Q 3W 4E 5E 6R 7E 8Q 9E 10Q 11R 12Q 13Q 14W 15W
Levels shown as recorded in ranked data; R is highlighted at its level-up points.
Cassiopeia Counters
Weak Against
38.9% 113 games 
40.1% 252 games 
40.3% 181 games 
40.9% 203 games 
43.0% 265 games Strong Against
53.7% 562 games 
52.9% 259 games 
52.0% 179 games 
51.6% 124 games 
51.0% 335 games Win rates are Cassiopeia's results against each champion, imported from op.gg.
Cassiopeia Build FAQ
Based on current ranked data (op.gg, patch 16.18.1), the strongest recorded Cassiopeia build in Middle goes Tear of the Goddess, Rod of Ages, Seraph's Embrace, Rylai's Crystal Scepter as core items, with a 47.66% win rate across 19,047 games.
The most played rune page runs Deathfire Touch (Sorcery) with Precision as the secondary tree.
Tear of the Goddess, Rod of Ages, Seraph's Embrace, Rylai's Crystal Scepter.
Based on real matchup data, Cassiopeia struggles most against Talon, Fizz, Kassadin.
Build and counter data is refreshed automatically every 48 hours from ranked game statistics.
